Uplifting Animal & Aliens

I came across this today and was reminded of this older episode. The future is coming upon us fast, some of the moral and ethical questions presented are now real-world issues to consider.
Personally, I think that furthering the understanding of how brains and intelligence in general develops is a great goal in research. However, I am not sure I am qualified to say what is right or wrong in this matter.
In any event, for your consideration and, civil discourse.

www.vox.com/future-perfect/2019/4/12/18306867/china-genetics-monkey-brain-intelligence

I agree that we need to further our research and understanding. I believe that everything is connected, not just our genes, but our consciousness as well. (interesting read: curiosity.com/topics/theres-no-such-thing-as-consciousness-according-to-philosopher-daniel-dennett-curiosity/)

I think we need to progress the understanding of intelligence as well as consciousness as our genes and their expressions are changed by our subjective experiences and how we perceive them. To push in one field without the consultation of the other is a delay imo, but the ethics your right are real world now. So what major considerations do you feel must be considered. Life itself makes many mistakes, people born with issues and deformations. So I feel our consideration of their subjective experience should be looked at in regards to altered life forms. What is the focus our programs aimed at helping people with disabilities and deformations? Quality of life and as much ability to live a pleasant life are top of the list.

This thread is a bit old but I'm new here and the topic fascinates me.
Does anyone know of an example from science fiction of uplifting happening in a realistic sense? 2001 is the obvious answer but I'm looking for something a bit more recent.

This series is a bit old, but it is a very good depiction of a future where humans uplift various species: en.wikipedia.org/wiki/Uplift_Universe

Oh boy I read that whole series!

I'd never heard of 'uplifting' or David Brin before these books.

Did he coin the term?

I believe so, yes.

I happen to like the idea of "uplifing" species, even if other people find reasons to be worried.

It should be noted that it is possible to talk to:
1. Dolphins using a computer translator (they can learn and use a pictographic language, they might also be more intelligent than the average human - more study is needed).
2. The Great Apes (they can learn and use sign language).
3. (I wish I still had the reference as this is unbelievable for most people) There was a song bird researcher who believed that he was close to figuring out the various languages that songbirds (Robins, Cardinals, etc) use. He believed that he had identified ~30,000 words per songbird species and that each songbird attempted to have/make-use-of a unique name (just like us). He claimed that a "tweet" is actually a full paragraph of information; that we are just too slow to recognize the individual words without using a computer to slow things down (and that birds are generally too fast to want to talk to us; try slowing down a video playback, it's painful).
4. There are companies which will try to sell you a pet collar which will translate the dog or cat's voice into (English). They claim that their translator is legit and not just a gimmick.

As for rough examples of some of the creatures I'd like to see after various creatures are uplifted:
www.animenewsnetwork.com/encyclopedia/anime.php?id=19402 (Anime: A Centaur's Life)
www.animenewsnetwork.com/encyclopedia/anime.php?id=5746 (Anime: Utawarerumono)
www.animenewsnetwork.com/encyclopedia/anime.php?id=12246 (Anime: Dog Days)
www.animenewsnetwork.com/encyclopedia/anime.php?id=16856 (Anime: Monster Musume)
www.animenewsnetwork.com/encyclopedia/anime.php?id=121 (Anime: Blue Submarine no. 6)
www.animenewsnetwork.com/encyclopedia/manga.php?id=3509 (Video Games and Mangas: The Zora and Gorons from "The Legend of Zelda" series)

I always imagine "placing a human brain on-top-of the animal brain" as in, "reconstruct" the lower parts of the brain (and all of the bio-chemistry, via genetic changes) so that the new sentient thinks like the animal (instincts, world-view, etc.) that it is supposed to represent / be based on, etc.

I expect that the only way to develop the requisite Genetic Engineering technology is to Try to Do It and then (after investigating numerous failures) actually Do It.
While I might change my hair color genes, or re-engineer molecular parts of my mitochondria, I certainly can't risk changing the way (my or your) brain works without having a deep understanding of exactly how the changes work (and thus a whole series of successful test subjects and a sizeable graveyard of failures, etc.) (I wouldn't want to change my mental processes unless I had well verified proof that the changes are advantageous; I must have at least a few successful human-level test subjects to evaluate).

• Also, it is impossible to build a meaningful computer model without at least some experimental data and even then, the model is only as good as the inputed data (without prior successes in X, there can be no trustworthy model concerning X).

What are your thoughts?
Also, would it be appropriate to discuss the engineering of (humans/humanoids) on these forums? I'd like to talk about specific genes and the adding of new gene loci, etc.